Pdf podophyllum hexandrum a perennial herb, bearing the common name. The root and underground stem rhizome are used to make medicine. This exoticlooking hybrid is a close cousin to our native may apple. Production of podophyllotoxin from podophyllum hexandrum. Production podophyllotoxin by root culture of podophyllum. Podophyllum article about podophyllum by the free dictionary. Common names include himalayan may apple and indian may apple. Carbon tetrachloride induced kidney and lung tissue damages. It forms dense colonies in open deciduous woodlands and other shaded sites. Podophyllum a genus of plants of the family podophyllaceae.
Plant profile for podophyllum kaleidoscope hybrid may. Podophyllum hexandrum s are becoming quite rare in their natural habitat, in fact, the plant is now considered endangered. Mayapple, podophyllum peltatum master gardener program. Files are available under licenses specified on their description page. Podophyllum pleianthum may be considered the big daddy of the genus, with flat, hexagonal disklike leaves of shiny green that can be twenty inches across. Podophyllum l an endergered and anticancerous medicinal. Podophyllum peltatum an overview sciencedirect topics. Podophyllum peltatum, commonly called mayapple, is a rhizomatous, native missouri wildflower that occurs in both moist and dry woodland areas throughout the state. Commercially exploitable sources of podophyllotoxin are few and currently it is obtained for drug use from dried rhizome and roots of podophyllum sps. The stems grow to 3040 cm tall, with palmately lobed umbrellalike leaves up to 2040 cm diameter with 39.
Pdf on jan 1, 2014, ishfaq hameed and others published podophylum hexandrum. Plants and their phytochemicals, especially with free radical scavenging. The one remaining species is podophyllum peltatum, with common names mayapple, american mandrake, wild mandrake, and ground lemon. Unlike our native podophyllum peltatum, podophyllum versipelle ssp.
Antioxidant and protective effect of ethyl acetate extract of. It can be a wonderful groundcover, outcompeting most weeds in a woodland garden or naturalized setting. Supplementation of the medium with both polyvinylpyrrollidone pvp and pectinase eliminated these problems. Radioprotective nature of podophyllum hexandrum himalayan mayapple. Overall, the parts used for medicinal purposes are mainly the. Podophyllum is also used to empty the bowels, kill parasitic worms in the intestine, and counteract snakebite. Podophyllum spotty dotty terra nova nurseries, inc. Sinopodophyllum is an herbaceous perennial plant in the family berberidaceae, described as a genus in 1979. Podophyllum versipelle ssp boreale aka chinese mayapple. Pdf podophyllum hexandrum aqueous extract as a potential. This page was last edited on 16 december 2019, at 19. This very choice plant has marbled bronze, trilliumlike leaves, which erupt through the ground like folded umbrellas.
Culinary plants, deer resistant plants, dry shade plants, pollinator plants, medicinal plants, ornamental seed or fruit, plants from china, wet shade plants, podophyllum versipelle, buy. Sep 17, 2019 podophyllum is highly poisonous when taken by mouth. Podophyllum definition of podophyllum by merriamwebster. Podophyllum hexandrum royle of family berberidaceae is an endangered medicinal plant. Podophyllum definition is the dried rhizome and rootlet of the mayapple that is used as a caustic or as a source of the more effective podophyllin. Podophyllum definition of podophyllum by the free dictionary. Podophyllum hexandrum is succulent erect herb, glabrous, up to 30 cm tall with creeping long knotty rhizomes. Gardens look out for hints of the beauty to come bemerging shoots, in their many wonderful shapes, are bringing life to dull scenes, lighting up trees and plants with promise peony bplump, with a perfect polish podophyllum hexandrum unwraps. Growing podophyllum hexandrum himalayan may apple from. It has been shown that ferulic acid and methylenedioxy substituted cinnamic acid are the enzymes involved in ptox synthesis. Podophyllum hexandrum offers radioprotection by modulating free radical flux. Sinopodophyllum hexandrum himalayan may applerhs gardening. Other common names himalayan may apple himalayan mandrake. October or the seeds placed in moist vermiculite in ziploc bags until sowing.
Sinopodophyllum hexandrum, taken in potatso national park, shangrila, yunnan. If youve only seen our native podophyllum peltatum, you have missed some of the great joys of the genus podophyllum. Dec 07, 2019 if you get podophyllum resin in the eyes, flush right away with cool water and get medical help. Podophyllum hexandrum offers radioprotection by modulating free. Podophyllum hexandrum health effects and herbal facts. In good moist soil this treasure is spectacular and very longlived. Currently, the commercial source of podophyllotoxin is the rhizomes and roots of podophyllum emodi wall. Podophyllum hexandrum offers radioprotection by modulating.
The perennial herb podophyllum hexandrum, bearing the common names himalayan mayapple or indian may apple, is native to the lower elevations in and surrounding the himalaya. These are very waxy and go on to produce small, fleshy, deep pink fruits in. Treating genital warts is done in a doctors office. Podophyllum spotty dotty get the latest free version of acrobat reader here. Hxs 45x45cm podophyllum peltatum is a rhizotomous, spreading perennial with palmate, sometimes mottled, leaves which push up through the soil in late spring like a furled umbrella. The peroxyl ion scavenging potentials of s1 and s2 were found to be comparable i. To learn more about this unique herbaceous perennial, read this article.
Pdf podophyllum hexandrum a versatile medicinal plant. Podophyllum veripellis and podophyllum hexandrum are two others with remarkable foliage. Development of suspension culture of podophyllum hexandrum. In the past, several species were included in the genus, but all but one have been transferred to other genera dysosma and sinopodophyllum. Mayapple is a native wildflower with distinctive, deeply lobed, umbrellashaped leaves. This valuable medicinal plant produces podophyllin which is an important anticancer drug. The species is hermaphrodite has both male and female organs. Nodding cupshaped white flowers develop in the leaf axils. It is low to the ground with glossy green, drooping, lobed leaves on its few stiff branches, and it bears a pale pink flower and bright redorange bulbous fruit.
The upper part of the stem bears two large, opposite, and longpetioled palmatipartite leaves and one drooping white flower measuring. Podophyllum resin topical for the skin is used to treat genital and anal warts in adults. Family berberidaceae genus podophyllum are rhizomatous perennials with lobed leaves, varying in shape from hexagon to starburst, with a central stem. Study of anticancer and antibacterial activities of podophyllum hexandrum as natural curatives javaid aftab1, ejaz aziz2, asad zulqarnain 1, mubeen tabish nasim, aamir sajjad 1,muhammad qamrosh zafar and riffat batool1 1university institute of biochemistry and biotechnology, pir mehr ali shah arid agriculture university rawalpindi, rawalpindi, punjab 46000, pakistan. Podophyllum hexandrum as a potential botanical supplement for the medical management of nuclear and radiological emergencies nres and free radical. Crystalline white flower cups produce enormous brilliantred fruits, as large as a bantams egg. Growing podophyllum hexandrum himalayan may apple from seed. It is in flower from may to june, and the seeds ripen from july to august. Reactive oxygen species ros and other free radicals intracellularly. Leaves alternate, palmate, up to 25 cm in diameter, deeply divided in 3. Genus podophyllum are rhizomatous perennials with lobed leaves, varying in shape from hexagon to starburst, with a central stem. Antioxidant research is an important area in the field. Podophyllum wikibooks, open books for an open world.
Podophyllum is an herbaceous perennial plant in the family berberidaceae, described as a genus by linnaeus in 1753. Factors influencing podophyllotoxin production in adventitious root. All structured data from the file and property namespaces is available under the creative commons cc0 license. Find the perfect podophyllum hexandrum, stock photo. Please be patient as pdf s may take a moment to load. Podophyllum versipelle ssp boreale chinese mayapple for.
It includes only one known species, sinopodophyllum hexandrum, native to afghanistan, bhutan, northern india, kashmir, nepal, pakistan, and western china gansu, qinghai, shaanxi, sichuan, tibet, yunnan. Deoxypodophyllotoxin dppt is extracted from podophyllum peltatum, podophyllum pleianthum, podophyllum emodi podophyllum hexandrum, and diphylleia grayi hu et al. Podophyllum prefers to be just slightly dry when dormant, so if condensation has formed on the inside of the bag you should open it, let it air out, then close it again. Radioprotective nature of podophyllum hexandrum himalayan. Aug 23, 2011 podophyllum hexandrums are becoming quite rare in their natural habitat, in fact, the plant is now considered endangered. Flower color is purplelavender and blooms in spring. The antioxidant potential of the plant extract under in vitro situations was evaluated by using two separate methods, inhibition of superoxide radical and hydrogen peroxide radical. Podophyllum hexandrum himalayan mayapple extract provides radioprotection by modulating the expression of proteins associated with apoptosis raj kumar, pankaj kumar singh, ashok sharma, jagdish prasad, ravinder sagar, surender singh, rajesh arora, rakesh kumar sharma. There are ethnobotanical records based on its healing properties in asian culture for the treatment of skin cancers as well as due to its purgative, emetic, cytotoxicity, antitumour and antileukaemic properties 11,19.
The one remaining species is podophyllum peltatum, with common names mayapple. Each plant bears a single stem crowned with one or two, large, very glossy, shallowlylobed 610 lobes each, umbrellashaped leaves to 1216 wide. The present study was conducted to evaluate the in vitro and in vivo antioxidant properties of aqueous extract of podophyllum hexandrum. Podophyllum hexandrum royle sinopodophyllum hexandrum royle t.
Radioprotective activities of podophyllum hexandrum trees for life. Podophyllum is highly poisonous when taken by mouth. Citeseerx document details isaac councill, lee giles, pradeep teregowda. Carbon tetrachloride ccl4 is a well known toxicant and exposure to this. Podophyllum hexandrum offers radioprotection by modulating free radical. Studies have shown that the podophyllum hexandrum is a difficult plant to grow indeed, and mass scale grow ops of the plant have so far proven a failure. A suspension culture of podophyllum hexandrum was established.
Podophyllum peltatum contains 45% podophyllum resin, whereas p. In pakistan, podophyllum hexandrum is on the verge of being endangered due. We have evaluated the effect of variation in aryltetralin lignans on the radioprotective properties of podophyllum hexandrum. American podophyllum consists of dried rhizomes and roots of p.
The sought after species and hybrids are those from china, with some remarkable coloring as well a attractive flowers in spring. Upright stems appear in spring, bearing huge umbrellashaped green leaves boldly marked with. A way of production podophyllotoxin by root culture of podophyllum hexandrum royle p. Podophyllum hexandrum aqueous extract as a potential free radical. Citeseerx original article podophyllum hexandrum offers. Growing podophyllum from seeds, including dysosma and. Podophyllum hexandrum or himalayan mayapple bankakari growing in the high himalaya. Nevertheless, some people take it orally for yellowed skin, liver ailments, fever, syphilis, hearing loss, and cancer. These free radicals and ros created in the plant cellorgan culture. They are easy to keep in moist vermiculite as long as were well cleaned. The popular cultivar spotty dotty is ah asian species, podophyllum delavayi is known as the chinese mayapple. Molecules free fulltext combined in vitro studies and. It also has numerous applications in modern medicine by virtue of its free radical. Podophyllum hexandrum an overview sciencedirect topics.
Leaves alternate, palmate, up to 25 cm in dimeter, deeply divided in 35 lobes, toothed, purple spotted. Podophyllum hexandrum, free radicals, ccl4, antioxidant activity, anticancer. The plants are sometimes included in the family berberidaceae. This is a shade loving, clumpforming perennial that typically grows to 1824 tall. The leaves are thick and textured, with prominent veins and often marbled or mottled in shades of green and brown. Mayapple is a native woodland plant that is widespread across most of eastern north america south to texas in zones 3 to 8. In the basis of a plantlets septic induced from m ature embryo of p. The hepatoprotective potential of podophyllum hexandrum extract was also evaluated in male wistar rats against carbon tetrachloride ccl 4induced liver damage.
Find the perfect podophyllum hexandrum stock photo. Podophyllum peltatum is the only species in this genus in the barberry family berberidaceae. Upright stems appear in spring, bearing huge umbrellashaped green leaves boldly marked with bronze and creamy silver. Antioxidant and protective effect of ethyl acetate extract. Podophyllum definition of podophyllum by medical dictionary. Podophyllum hexandrum himalayan may apple pfaf plant database. Study of anticancer and antibacterial activities of. From a single stem, each plant grows 1218 tall and features one or two, deeplydivided, palmatelylobed, umbrellalike, pale green leaves to 12 diameter. Floral characteristics flowers are white to pinkish in colour, 4. They are woodland plants, typically growing in colonies derived from a single root. This herbaceous perennial typically grows in colonies from a single root in open deciduous forests and shady fields, riverbanks and roadsides. As the cultures grew, reduction in cell viability, biomass and product yield were associated with browning of culture medium, clumping of cells and drop in medium ph.
Pretreated rats were given ethyl acetate extract at 20, 30 and 50 mgkg dose prior to ccl 4 administration 1 mlkg, 1. Podophyllum resin topical is not for use inside the vagina, cervix, rectum, or urethra the tube for passing urine out of your bladder. Plant your podophyllum in part shade to full shade in loose and airy, humusrich, moist but welldraining woodland. The tribe podophylleae, consisting of podophyllum including sinopodophyllum and dysosma and diphylleia, is rich in various podophyllotoxin lignans zhao et al. Pdf podophyllum hexandrum as a potential botanical.
Podophyllum hexandrum royle, commonly known as indian may apple. Podophyllum hexandrum emodi seeds sinopodophyllum hexandrum syn. The genus podophyllum consists of low perennial herbs that have a long, creeping rootstock. Podophyllum is a genus of six species of herbaceous perennial plants in the family berberidaceae, native to eastern asia five species and eastern north america one species. Another woodlander, podophyllum hexandrum exemplifies the insurgence of spring. In the great continental divorce about 250 million years ago, most of the really cool mayapple species were on the wrong side of the great crack and got stuck in china. Podophyllum hexandrum aqueous extract as a potential free radical scavenger. It consists of the dried rhizome and root of podophyllum hexandrum royle podophyllum emodi. Podophyllum hexandrum wikispecies, free species directory. The full text of this article is available as a pdf 114k. In recent studies, we concluded that the leaf blades of the north american mayapple p. Podophyllum pleianthum, commonly called chinese mayapple, is native to central and southeastern china. It is grow in forest of the himalaya from kashmir, tibet, afghanistan.
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